BioTech Mag Search: Protein
Sugars that coat proteins are a possible drug target for pancreatitis
LA JOLLA-Pancreatitis is an inflammation of the pancreas that accounts for 275,000 hospitalizations in the United States annually. Patients who suffer from hereditary...
46 minutes ago - San Diego Biotechnology
Directed protein evolution with CRISPR-Cas9
New area of application for gene scissors: Optimized proteins for biomedical research.
2 hours ago - ScienceDaily
How a protein can inhibit cancer development in mice
In a new study, researchers have discovered how the protein PP2A can inhibit tumor growth in mice. The protein turns off an enzyme that stimulates cell growth, thus inhibiting...
2 hours ago - ScienceDaily
Identification of biochemically neutral positions in liver pyruvate kinase
Abstract Understanding how each residue position contributes to protein function has been a long‐standing goal in protein science. Substitution studies have historically...
7 hours ago - Wiley
Scientists synthesize tick spit protein for first time
Using the properties of naturally occurring proteins offers huge potential for new medicines. Charlotte Franck in Professor Richard Payne's lab has for the first time made the...
11 hours ago - Phys
HECNet: a hierarchical approach to Enzyme Function Classification using a Siamese Triplet Network
AbstractMotivationUnderstanding an enzyme's function is one of the most crucial problem domains in computational biology. Enzymes are a key component in all organisms and many...
1 day ago - Oxford Journals
An under-researched mechanism in the fast-moving field of epigenetics
A key epigenetic mark can block the binding of an important gene regulatory protein, and therefore prohibit the gene from being turned off, a new UNSW study in CRISPR-modified...
1 day ago - Phys
RDE-3 found to add pUG tails to targets of RNA interference and to transposon RNAs
A team of researchers from Harvard Medical School, Nanjing Agricultural University and the University of Wisconsin has found that the protein RDE-3 in nematode worms adds pUG...
1 day ago - Phys
A cross-sectional study exploring disease characteristics and phylogenetic nature of human cytomegalovirus among infected neonates with congenital nephrotic syndrome
Abstract Background Congenital nephrotic syndrome is a rare but serious condition which affects neonates and is caused by monogenic defects of glomerular structural proteins or...
1 day ago - Springer
A tail of CRY selectivity
Nature Chemical Biology, Published online: 22 May 2020; doi:10.1038/s41589-020-0531-z The discovery of selective modulators of two Cryptochrome isoforms, CRY1 and CRY2, permits...
1 day ago - ACS Division of Biological Chemistry - 7 articles
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Site of LUX-ZEPLIN Dark Matter Search Project Carefully Ramps Up Science Work
A photomultiplier tube array that is part of the LUX-ZEPLIN experiment at the Sanford Underground Research Facility in Lead, South Dakota. The photomultiplier tubes are...
Viacyte Adds $27M to Move Ahead Trio of Stem Cell Diabetes Treatments
Privately held biotech ViaCyte has banked $27 million, the majority an installment of cash from a tranched $80 million Series D financing round it closed in late 2018. The...
COVID-19 Sparks New Opportunities for Digital Health Companies
Clinicians and regulators are rethinking how healthcare is provided amid precautions prompted by COVID-19. In-person physician visits don't fit within the physical distancing...
Bone‐Inspired Tube Filling Decellularized Matrix of Toad Cartilage Provided...
Because of its rich cartilage‐like matrix and low immunogenicity, the decellularized toad bone matrix is processed as hydrogel. Mesenchymal stem cells in dBECM hydrogel are...
Crystal Contact Engineering Enables Efficient Capture and Purification of an...
The crystallization of an industrial enzyme from crude microbial lysate resulting in high yield and purity is reported. Significantly enhanced crystallization is enabled by...
Micropipette Aspiration‐Based Assessment of Single Channel Water Permeability
The method works at low reconstitution densities of water conducting channels and is not limited by unstirred layers. It allows for simultaneous measurements of channel...
Modeling the Residence Time Distribution of Integrated Continuous Bioprocesses
A thorough understanding of mass flows in the process is required by the Food and Drug Administration in their draft on guidelines for continuous integrated biomanufacturing. A...
Anything but Conventional Chromatography Approaches in Bioseparation
Anything but conventional chromatography is an increasingly relevant trend in downstream processing. These alternative approaches are put in perspective considering past...
Molecular Targets for the Testing of COVID‐19
RNA and proteins of a Betacoronavirus virion as well as virus induced antibodies can be used as molecular biomarkers for viral infection. This paper describes the principle of...
Senior Director, Quality Assurance - GMP - Mapp Biopharmaceutical - San...
Experience overseeing GMPs at third-party locations in a small or mid-sized Biotechnology company. Senior Director, Quality Assurance - GMP.From Mapp Biopharmaceutical - Wed...