• Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study

    27 days ago - By Springer

    Abstract
    Recent genomic studies have shed light on the biology and inter-tumoral heterogeneity underlying pineal parenchymal tumors, in particular pineoblastomas and pineal parenchymal tumors of intermediate differentiation. Previous reports, however, had modest sample sizes and lacked the power to integrate molecular and clinical findings. The different proposed molecular group structures also highlighted a need to reach consensus on a robust and relevant classification system. We performed a meta-analysis on 221 patients with molecularly characterized PBs and PPTIDs. DNA methylation...
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