• Bone‐Inspired Tube Filling Decellularized Matrix of Toad Cartilage Provided an Osteoinductive Microenvironment for Mesenchymal Stem Cells to Facilitate the Radius Defect Repair of Rabbit

    1 month ago - By Wiley

    Because of its rich cartilage‐like matrix and low immunogenicity, the decellularized toad bone matrix is processed as hydrogel. Mesenchymal stem cells in dBECM hydrogel are perfused to a hollow tube made from hydroxyapatite and poly. After surgically implanting dBECM + MSCs‐PGA + HA to the radius defect of rabbit, the cortex and medullary cavity recanalization are well recovered.
    Abstract
    Toad bone not only contains the rich cartilage‐like matrix but also presents low immunogenicity. It is inferred that decellularized toad bone matrix may provide the more profitable osteoinductive...
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