• Dynamic Meta-Storms enables comprehensive taxonomic and phylogenetic comparison of shotgun metagenomes at the species level

    8 days ago - By Oxford Journals

    AbstractMotivationAn accurate and reliable distance among shotgun metagenomes is fundamental to deducing the beta-diversity of microbiomes. To compute the distance at the species level, current methods either ignore the evolutionary relationship among species or fail to account for unclassified organisms that cannot be mapped to definite tip nodes in the phylogenic tree, thus can produce erroneous beta-diversity pattern.ResultsTo solve these problems, we propose the Dynamic Meta-Storms algorithm to enable the comprehensive comparison of metagenomes on the species-level with both taxonomy...
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