• PolyCluster: Minimum Fragment Disagreement Clustering for Polyploid Phasing

    1 month ago - By IEEE/ACM

    Phasing is an emerging area in computational biology with important applications in clinical decision making and biomedical sciences. While machine learning techniques have shown tremendous potential in many biomedical applications, their utility in phasing has not yet been fully understood. In this paper, we investigate development of clustering-based techniques for phasing in polyploidy organisms where more than two copies of each chromosome exist in the cells of the organism under study. We develop a novel framework, called PolyCluster, based on the concept of correlation clustering...
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