• SurfaceGenie: a web-based application for prioritizing cell-type specific marker candidates

    3 days ago - By Oxford Journals

    AbstractMotivationCell-type specific surface proteins can be exploited as valuable markers for a range of applications including immunophenotyping live cells, targeted drug delivery, and in vivo imaging. Despite their utility and relevance, the unique combination of molecules present at the cell surface are not yet described for most cell types. A significant challenge in analyzing ‘omic' discovery datasets is the selection of candidate markers that are most applicable for downstream applications.ResultsHere, we developed GenieScore, a prioritization metric that integrates a...
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