• How accumulating useful genes helps older yeast fare better in tougher times

    7 days ago - By Phys

    Genome amplification, whereby organisms bump up the number of copies of beneficial genes in response to environmental stresses, is implicated in diseases such as cancer and also in ageing. Researchers in the Babraham Institute's Epigenetics research programme have used yeast to learn more about how satellite DNA circles are formed to carry amplified genes, how the gene duplication is specific to the environmental pressure and the effects of age. Their research is published today in the journal PLOS Biology.
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  • Researchers use genomics to discover potential new treatment for parasite disease

    7 days ago - By Phys

    Using innovative RNA sequencing techniques, researchers at the University of Maryland School of Medicine Institute for Genome Sciences identified a promising novel treatment for lymphatic filariasis, a disabling parasitic disease that is difficult to treat. The potential new therapy is an experimental cancer drug called JQ1 and targets proteins found prominently in the worm's genome; it appears to effectively kill the adult worms in a laboratory setting, according to the study which was published today in the journal mSystems.
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