• MiR-195 inhibits migration, invasion and epithelial-mesenchymal transition of endometrial carcinoma cells by targeting SOX4

    8 days ago - By Journal of Biosciences

    Abstract
    MicroRNAs have been identified as potential biomarkers for endometrial carcinoma diagnosis, prognosis and therapy. The purpose of the present study was to investigate the detailed role and molecular mechanism of miR-195 in EC metastasis. qRT-PCR assay was performed to assess the expression of miR-195 and SRY-related high-mobility group box 4 mRNA in EC tissues and cells. The levels of N-cadherin, Vimentin, E-cadherin and SOX4 protein were determined by western blot. SOX4 protein expression in EC tissues was also determined by Immunohistochemistry experiment. Transwell assay was...
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